Glycemic control in critically ill patients

Glycemic control in critically ill patients.

Hyperglycemia is common in critically ill patients and can be caused by various mechanisms, including nutrition, medications, and insufficient insulin. In the past, hyperglycemia was thought to be an adaptive response to stress, but hyperglycemia is no longer considered a benign condition in patients with critical illnesses. Indeed, hyperglycemia can increase morbidity and mortality in critical...

Tight glycemic control in critically ill adults.

Tight Glycemic Control in Critically Ill Patients Reply

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Tight Glycemic Control in Critically Ill Children.

BACKGROUND In multicenter studies, tight glycemic control targeting a normal blood glucose level has not been shown to improve outcomes in critically ill adults or children after cardiac surgery. Studies involving critically ill children who have not undergone cardiac surgery are lacking. METHODS In a 35-center trial, we randomly assigned critically ill children with confirmed hyperglycemia (...

Software-guided insulin dosing: tight glycemic control and decreased glycemic derangements in critically ill patients.

OBJECTIVE To determine whether glycemic derangements are more effectively controlled using software-guided insulin dosing compared with paper-based protocols. PATIENTS AND METHODS We prospectively evaluated consecutive critically ill patients treated in a tertiary hospital surgical intensive care unit (ICU) between January 1 and June 30, 2008, and between January 1 and September 30, 2009. Pap...